Los Angeles Rams vs. San Francisco 49ers Betting Odds, Analysis, NFL Pick

September 8, 2016   ·     ·   Jump to comments

Even as the San Francisco 49ers have regressed since their most recent Super Bowl appearance, they've remained quick starters; the Niners are 5-0 both straight up and against the spread over their last five season openers.
This year San Francisco opens with a renewal of a great West Coast football rivalry when it hosts the Rams of Los Angeles on Monday night at Levi's Stadium in Santa Clara.
Point spread: Rams opened as 2.5-point favorites; the total was 47 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
NFL pick, via Odds Shark computer: 23.0-19.4 49ers (NFL picks on every game)
Why the Rams can cover the spread
Los Angeles is coming off a 7-9 season that had the potential to be better. The Rams lost four games by six points or fewer, two of those in overtime, and three times while holding opponents to 19 points or fewer. They also beat Seattle twice and Arizona once, a...

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